I don't prefer to use insecticides but last year I lost both plants to yellow vine diseases which is spread by cuke beetles and and squash bugs. A couple of years before that I lost a very nice 1789 Wallace plant to the same disease. Last season I only saw one squash bug in the patch all season and didn't see any cuke beetles. It just takes one infected squash bug to end a season early however.
Last season I sprayed, but this season I'm going to spray and also add a systemic to the mix. That should give me better coverage. For the contactants I only spay in the evening, to give the bees a better change. With the rains mostly done and warmer weather happening I suspect we are going to see a lot more bugs coming out.